========================================================= How to browse multi-dimensional genomics data in Gitools? ========================================================= Simple table: Gitools accepts a matrix format (.tdm) that contains various values per cell - or in other words multi-value matrices. This is especially helpful for browsing genomic data as nowadays study data is being released with expression, mutation, CNA and more data for each patient. Files/Data needed ----------------- For whatever data you want to browse, you need to prepare a :ref:`tdm`. For genomics data it may look like this: ========== ======= =========== ===== ========= column row expression CNA mutation ========== ======= =========== ===== ========= patient_01 gene_A 8.5 0 0 patient_01 gene_B 2.3 -2 0 patient_02 gene_A 6 0 1 patient_02 gene_B 5 0 0 patient_03 gene_A 12.1 2 0 patient_03 gene_B 4.9 0 1 ========== ======= =========== ===== ========= This is an example with three columns and two rows. Each cell has three data values. **Download this example matrix**: :download:`files/multivalue-matrix-example.tdm`. Browse in Gitools ----------------- .. image:: img/gitoolsviz.png :width: 40% :align: right :alt: Gitools screenshot Select the option *File -> Open -> Heatmap* In the dialog that pops up select as file Filter (the lowest box) one of the following two options: - Multivalue data matrix (tdm, tdm.gz) - Multivalue data matrix (\*.\*) Once the heatmap is opened in Gitools, go click on the dimension of data you want to see in the **details dialog** to the left (see *Dimension selector* in the screenshot to the right)